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Director Oligo API Production

Bachem is a listed technology-based company focused on peptide chemistry. The company provides a full range of services to the pharma and biotech industries. It specializes in the development of innovative, efficient manufacturing processes and the reliable production of peptide-based active pharmaceutical ingredients. A comprehensive catalog of biochemicals and exclusive custom syntheses for research labs complete the service portfolio. Headquartered in Switzerland with subsidiaries in Europe, the US and Asia, the group has a global reach with more experience and know-how than any other company in the industry. Towards its customers, Bachem shows total commitment to quality, innovation and partnership.

In order to continue our organic growth, we are constantly looking for talent.

Bachem is extending its technology platform to include GMP compliant manufacturing of oligonucleotide based molecules such as double stranded RNAs, antisense gapmers, aptamers and others.


The position


This is a new, high-profile, senior role within Bachem’s production operation. The Department Head, Oligonucleotide API Production will be a key member of the Oligonucleotide management team and lead the design, installation and qualification of a large-scale manufacturing line for nucleic acid-based APIs at Bachem’s headquarters facility in Bubendorf, Switzerland. This individual will hire, form and lead an entire production team focusing on the efficient, GMP compliant and timely manufacturing of custom molecules. Functions and responsibilities of the role include:


  • Design, installation and qualification of a large-scale manufacturing line (up- and downstream) for nucleic acid-based APIs
  • Recruitment and formation of a new department within Bachem’s Production Organization for oligonucleotide-based APIs
  • Lead the large-scale manufacturing operations and take on responsibility for the timely and compliant custom project work of the department
  • Liaise with the Department Head, Oligonucleotide Process R&D on custom project work and continuous improvement of manufacturing processes and processing innovations  
  • Support business development activities and technical interface in the communication with clients in global biotech and pharma
  • Reports into Senior Operations and Business Management


Your Profile


Interested candidates should be able to offer hands-on experience in the GMP-compliant production of large biomolecules, ideally nucleic acid based APIs. Your technical expertise includes chemical synthesis (solid phase) or biologics production, ion-exchange chromatography and ultrafiltration. In addition, we value the following skills and attributes:


  • Master or PhD in Biotechnology, Chemistry or Chemical Engineering
  • Entrepreneurial spirit and readiness to work in a fast-paced environment
  • Proven leadership skills and people management experience
  • Experience in handling big CAPEX projects
  • Working knowledge of SAP, SFDC, MS-Project applications
  • Willingness to present at specialized trade shows
  • Excellent communication and presentation skills in English and German
  • Ability to travel occasionally to meetings with clients and specialized trade shows


Our Offer


We offer a fascinating and challenging function in a dynamic environment, which guarantees diversity and versatility. In addition, we offer you the opportunity to work in an innovative environment and with a stable, motivated team. If this opening draws your attention, then we look forward to receiving your complete application.


Are you interested?


Please submit your application with full supporting documents (motivation letter, CV, testimonials, diplomas) via our recruiting tool to Mr. André Karrer (Senior HR Business Partner).