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Group Leader R&D

Bachem is a listed technology-based company focused on peptide chemistry. The company provides a full range of services to the pharma and biotech industries. It specializes in the development of innovative, efficient manufacturing processes and the reliable production of peptide-based active pharmaceutical ingredients. A comprehensive catalog of biochemicals and exclusive custom syntheses for research labs complete the service portfolio. Headquartered in Switzerland with subsidiaries in Europe, the US and Asia, the group has a global reach with more experience and know-how than any other company in the industry. Towards its customers, Bachem shows total commitment to quality, innovation and partnership.

In order to continue our organic growth, we are constantly looking for talent.

The position

This is a new role within Bachem’s R&D operation. The Group Leader Oligonucleotides is responsible for the development of cost efficient and scalable production processes of therapeutic oligonucleotides at Bachem’s headquarters facility in Bubendorf, Switzerland. The individual will lead a team of two or more technicians focusing on the GMP compliant and timely manufacturing of custom molecules.


Functions and responsibilities

  • Perform process development for the manufacturing of oligonucleotides (solid phase synthesis, chromatographic purification, lyophilization).
  • Lead a team of two or more laboratory technicians. Distribute workload, train, develop and manage employees. Routinely maintain/organize work areas and other designated areas at the manufacturing facility.
  • Evaluate, install, operate and maintain equipment for manufacturing and in-process testing.
  • Represent R&D in project teams. Compile and present scientific data in meetings with internal and external customers as well as in specialized trade shows.
  • Perform project planning and budgeting.
  • Initiate raw material order-requests. Receive raw materials, coordinate with QA/QC and Material Management for material release and monitor raw material inventories.
  • Write and suggest improvements for Standard Operation Procedures (SOPs), Master Batch Records (MBPRs) and other related GMP documents.
  • Follow and maintain GMP Documentation System. Initiate, investigate and closure of deviations, CAPAs, investigations, reports and related documents.


Your profile

  • PhD in chemistry, chemical engineering or biotechnology
  • Proven hands-on experience in organic synthesis, preferably in the synthesis and purification of oligonucleotides
  • Excellent communication and presentation skills in English and German
  • Proven leadership skills and people management experience
  • Entrepreneurial spirit and readiness to work in a fast-paced environment


In addition, we value the following skills and attributes

  • Familiar with GMP requirements for the production of APIs
  • Working knowledge of SAP, SFDC, and MS-Project applications


Our offer

We offer a fascinating and challenging function in a dynamic environment, which guarantees diversity and versatility. In addition, we offer you the opportunity to work in an innovative environment and with a young and motivated team. If this opening draws your attention, then we look forward to receiving your complete application.


Please submit your application with full supporting documents (motivation letter, CV, testimonials, diplomas) via our recruiting tool to Mr. André Karrer (Senior HR Business Partner).